Cyproheptadine is a first-generation anti-histamine used in the treatment of allergic reactions.
Mode of Action
Cyprohepatadine competitively inhibits the H1 receptor, mediating bronchial constriction, smooth-muscle contraction, edema, hypotension, CNS depression, and cardiac arrhythmias; it prevents histamine release in blood vessels and is more effective in preventing histamine response than in reversing it.
Adverse Drug Reactions
Anorexia, arrhythmias, blurredvision, cholestasis, CNS depression, dizziness, drowsiness, deep sleep, coordination disturbances, euphoria, mood changes, psychosis, seizures, neuropathy, myopathy, tremors, visual disturbances, vertigo, diaphoresis, headache, eczema, epigastric distress, dysuria hepatitis, hepatic failure, hepatic function abnormality, hypotension, hypertension, insomnia, nasal stuffiness, nausea, palpitation, arrhythmias, bowel disturbances, paresthesia, pruritus, thickening of bronchial secretions, tightness of chest, faintness, urinary retention, wheezing